First Movie Of An Entire Brain’s Neuronal Activity — The Physics arXiv Blog — Medium

First Movie Of An Entire Brain’s Neuronal Activity — The Physics arXiv Blog — Medium: ...Schrödel, Prevedel and co developed a way to ensure that the genes only fluoresce in the nucleus of each neuron. That makes active neurons much easier to tell apart...

...light sculpting. This works by bouncing the spot of laser light off a grating that stretches it out. This creates a disc of light that images an area of the brain in one go rather than a single point. In affect, it produces a cross-sectional image of brain activtiy.

The advantage is that the light disc need only be scanned in one direction to capture the whole volume of the brain. And this can be done at a rate that allows the team to film the neuronal activity of the entire brain at a rate of 80 frames per second.