Digital holographic microscopy allows for 50 times better resolution in viewing neurons | KurzweilAI: The technique accurately visualizes the electrical activities of hundreds of neurons simultaneously, at up to 500 images per second — without damaging them with electrodes...
To understand how DHM works, imagine a large rock in an ocean of perfectly regular waves. As the waves deform around the rock and come out the other side, they carry information about the rock’s shape. This information can be extracted by comparing it to waves that did not smash up against the rock, and an image of the rock can be reconstructed.
DHM does this with a laser beam by pointing a single wavelength at an object (in this case, neurons), collecting the distorted wave on the other side, and comparing it to a reference beam.
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