Math researcher illuminates cellular basis of neural impulse transmission: "The results of this work showed that the calcium current through an N-type channel was larger in comparison to calcium channels that are not involved in synaptic transmission, contrary to the currently accepted channel conductance hierarchy.
Furthermore, the authors' modeling work showed that the current through a single open N-type calcium channel may be sufficient to enable neurotransmitter release. These results demonstrate the degree to which N-type calcium channel properties are adapted for their role in synaptic transmission, and also shed light on the highly localized nature of intra-synaptic calcium signaling."
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