Exposing a Galaxy within the Brain - Technology Review: Smith and collaborators first sliced thin pieces of brain tissue and then stained the slices with groups of three different antibodies. Each antibody was designed to bind to a specific type of protein found in different types of synapses and to glow a certain color, with 17 different antibodies in all...
These individual pictures were then stitched together using specialized software also designed in Smith's lab, creating a three-dimensional image of the section of brain tissue. The research was published this week in the journal Neuron.
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